Study of Platelet Population Changes Under Circulatory Support With ECMO

Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.

NCT Number	NCT07334457
Lead Sponsor	University Hospital, Strasbourg, France
Conditions	Cardiac Failure, Respiratory Failure
Enrollment	75 participants
Start Date	2025-03-11
Primary Completion	2027-03 (estimated)
Study Completion	2027-03-11 (estimated)
Updated on ClinicalTrials.gov	2026-01-12