Clinical Trial

Comparison of Preoxygenation Techniques in Healthy Volunteers With Monitoring of End-tidal Oxygen Fraction (FeO₂) and Oxygen Reserve Index (ORI)

Study acronym: OXYGAME1
Completed
View on ClinicalTrials.gov →
Summary
The objective of this physiological study is to compare two preoxygenation techniques (non-invasive ventilation combined with high-flow nasal oxygen versus non-invasive ventilation alone) by monitoring end-tidal oxygen fraction (FeO₂) and the Oxygen Reserve Index (ORI) during 3 minutes of preoxygenation in healthy volunteers.
Protocol Amendment History 4 changes
critical Trial completed 2026-05-15
notable Primary completion moved earlier: 2027-02 -> 2026-04-29 2026-05-15
minor Completion moved earlier: 2027-08 -> 2026-04-29 2026-05-15
critical Recruitment opened 2026-03-31
Trial Details
NCT Number NCT07334041
Lead Sponsor Centre Hospitalier Régional d'Orléans
Conditions Healthy
Enrollment 30 participants
Start Date 2026-03-09
Primary Completion 2026-04-29 (estimated)
Study Completion 2026-04-29 (estimated)
Updated on ClinicalTrials.gov 2026-05-14