The Effects of Vibration on Lower Limb Muscle Strength, Functional Status, and Psychological Health in Stroke Patients

The goal of this clinical trial is to the effect of vibration training on lower limb muscle strength, functional status and psychological health of stroke patients. The main questions it aims to answer are: * Lower limb muscle strength was measured using the Medical Research Council Manual Strength Test. * Functional status was measured using Postural Assessment Scale for Stroke, and the Barthel scale. * Psychological health was measured using the Hospital Anxiety and Depression Scale. Participants will be randomly assigned to four groups: 1. Control group: Receives only rehabilitation training and standard treatment. 2. Comparison group: Receives rehabilitation training, standard treatment, and a 30-minute stationary cycling intervention during hospitalization for 5 days. 3. Experimental group 1: Receives rehabilitation training, standard treatment, and a 30-minute wearable lower-limb high-frequency, low-amplitude vibration therapy during hospitalization for 5 days, followed by 30 minutes of stationary cycling. 4. Experimental group 2: Receives rehabilitation training, standard treatment, and a 30-minute vertical lower-limb low-frequency, high-amplitude vibration therapy during hospitalization for 5 days, followed by 30 minutes of stationary cycling. All participants will undergo an initial measurement within 4 hours of admission, followed by the second and third measurements after the 5-day intervention and on the day of discharge, respectively.

NCT Number	NCT07333456
Lead Sponsor	Tri-Service General Hospital Collaborators: National Science and Technology Council, Taiwan
Conditions	Stroke
Enrollment	115 participants
Start Date	2022-01-14
Primary Completion	2025-04-26 (estimated)
Study Completion	2025-04-26 (estimated)
Updated on ClinicalTrials.gov	2026-02-10