Sequential bpMRI for Suspicious Prostate Lesions

This study aims to establish a prospective exploratory cohort and database to observe the dynamic evolution of bi-parametric MRI (bpMRI). Investigators intend to study the clinical utility of sequential MRI combined with prostate biopsy in the diagnosis of prostate cancer. Specifically, by utilizing bpMRI findings and their dynamic changes to guide the timing of biopsies, investigators aim to avoid unnecessary procedures. Furthermore, the safety and efficacy of this strategy will be assessed through long-term follow-up, ultimately promoting the precision diagnosis and treatment of prostate cancer.

NCT Number	NCT07332832
Lead Sponsor	Peking University First Hospital Collaborators: Shanghai East Hospital of Tongji University
Conditions	Prostate Cancer
Enrollment	1,000 participants
Start Date	2026-02-01
Primary Completion	2028-12-31 (estimated)
Study Completion	2029-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-02-18