Additional Effects of Sensory Integration Along With Focused Regimen Exercises on Kinaesthesia & Proprioception in Diabetic Peripheral Neuropathy.

This study aims to evaluate Additional Effects of sensory integration along with focused regimen exercises on kinaesthesia \& proprioception in Diabetic peripheral neuropathy Peripheral neuropathy a Condition occur when the nerves outside the brain and spinal cord are damaged. It affects the upper and lower extremity. The estimated prevalence of peripheral neuropathy in patients with diabetes in Pakistan is around 43%. The condition is more common in those who have poorly controlled diabetes. Signs and symptoms include Numbness, tingling, Pain, which may be burning, stabbing or shooting, unusual touch-based sensations (dysesthesia), Muscle weakness, Total or partial loss of sensation in feet, like not feeling pain from foot injuries, loss of position and movement sense. Kinaesthesia and proprioception are defined as awareness of the position and movement of the body parts by sensory organs (proprioceptors) in the muscles and joints. Uncoordinated movement, clumsiness, poor postural control are common symptoms. Multiple treatment options are available for training kinaesthesia and proprioception impairments in peripheral neuropathy including use of electrotherapeutic agents, proprioception exercises, sensory integration, and focused regimen exercises. Current study will be RCT on 40 participants recruited on the basis of inclusion criteria which are Diagnosed as Type 2 Diabetic peripheral neuropathy (DPN) by physician in the age group of 45-65 Years in Both genders with type 2 Diabetes. Patients with moderate neuropathy according to Michigan nephropathy screening tool and having the ability to walk with or without assistance. Participants will be randomly and equally divided into two groups; group A will be receiving focused regimen exercises and group B will be receiving both sensory integration exercises along with focused regimen exercises. The treatment will be given for 45min, 3 days a week for total of 8 weeks. The assessment will be conducted at baseline by (Michigan neuropathy screening tool, Brief kinaesthesia test (BKT), Modified Clinical Test of Sensory Interaction for balance (mCTSIB), Norfolk quality of life for diabetic neuropathy), and final assessment will be conducted after 8 weeks of treatment.

NCT Number	NCT07332364
Lead Sponsor	Foundation University Islamabad
Conditions	Diabetic Neuropathy, Proprioception
Enrollment	30 participants
Start Date	2025-09-15
Primary Completion	2025-10-26 (estimated)
Study Completion	2025-12-20 (estimated)
Updated on ClinicalTrials.gov	2026-01-15