Evaluation of Removable Appliances and Clear Aligners in Early Orthodontic Treatments During the Mixed Dentition Period

This prospective study aims to compare two different orthodontic treatment modalities-clear aligners and removable appliances-in children aged 6 to 12 years during the mixed dentition period. The primary focus of the research is to evaluate treatment-related changes in oral hygiene status assessed using the Simplified Oral Hygiene Index (OHI-S), oral health-related quality of life, pain and anxiety levels, and speech function. In addition, orthodontic treatment need will be assessed using the Index of Orthodontic Treatment Need (IOTN), including both the Dental Health Component (DHC) and Aesthetic Component (AC). By assessing multiple dimensions associated with early orthodontic intervention, the study seeks to provide a comprehensive understanding of how different appliance types influence clinical, functional, and psychosocial outcomes in pediatric patients.

NCT Number	NCT07331090
Lead Sponsor	Neslihan Atmaca Collaborators: Marmara University
Conditions	Malocclusion, Crossbite
Enrollment	24 participants
Start Date	2024-05-15
Primary Completion	2024-11-20 (estimated)
Study Completion	2025-05-15 (estimated)
Updated on ClinicalTrials.gov	2026-06-18