Clinical Trial

Assessment of Cytotoxicity, Genotoxicity

Completed
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Summary
Goal: The goal of this observational study is to evaluate the genotoxic and cytotoxic effects of OPG and CBCT on exfoliated buccal mucosal cells Main question: Does CBCT cause greater genotoxic and cytotoxic effects on buccal mucosal cells compared with OPG? Buccal epithelial cells were gently exfoliated from participants scheduled to undergo OPG or CBCT imaging. Samples were collected twice-immediately before exposure and again 10-12 days afterward. All participants provided written informed consent prior to inclusion in the study.
Trial Details
NCT Number NCT07330401
Lead Sponsor Yaxin Wang
Conditions Genotoxicity, Cytotoxicity, Ionizing Radiation Exposure, Dental X-Ray Exposure
Enrollment 60 participants
Start Date 2024-10-01
Primary Completion 2025-07-01 (estimated)
Study Completion 2025-09-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-09