Clinical Trial

Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients

Study acronym: CHAIN-T
Not Yet Recruiting
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Summary
The purpose of this study is to evaluate whether the administration of 5 ml/kg of colloid solution prior to anesthesia induction, compared with 5 ml/kg of lactated Ringer's solution, can reduce hemodynamic fluctuations during the induction period (defined as the first 15 minutes after induction) in patients undergoing Transcatheter Aortic Valve Replacement (TAVR).
Protocol Amendment History 2 amendments
This ClinicalTrials.gov record has been amended 2 times since 2025-12-29; most recent amendment 2026-02-25.
Trial Details
NCT Number NCT07329660
Lead Sponsor Air Force Military Medical University, China
Conditions Transcatheter Aortic Valve Replacement, Hemodynamic Stability, Anesthesia Induction
Enrollment 116 participants
Start Date 2026-02-16
Primary Completion 2026-12-31 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-02-27