Analysis of the Role of IgE Proteoforms in Health and Disease

The goal of this observational study is to evaluate the role of IgE proteoforms in healthy volunteers and in patients with type I allergy, patients with chronic spontaneous urticaria, patients with a recent history of anaphylaxis, patients with mastocytosis, patients with hereditary alpha tryptasemia, patients with X-linked agammaglobulinemia (XLA), and patients undergoing desensitization for venom or medication allergy.

NCT Number	NCT07328178
Lead Sponsor	KU Leuven
Conditions	Anaphylaxis, Mastocytosis, X-linked Agammaglobulinaemia, Venom Allergy, Chronic Spontaneous Urticaria (CSU), Type I Allergy, Medication Allergy, Healthy Control +1 more
Enrollment	200 participants
Start Date	2025-01-01
Primary Completion	2029-01-01 (estimated)
Study Completion	2029-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-09