The Effectiveness of Oxygen Reserve Index in Early Detection of Desaturation in Geriatric Patients Scheduled for Oncological Surgery

This prospective observational study aims to evaluate the relationship between the Oxygen Reserve Index (ORI) and tolerable apnea time in geriatric patients undergoing elective oncologic surgery under general anesthesia. Patients aged 65 years and older will be monitored using standard anesthesia monitoring and Masimo Rainbow SET® Pulse CO-Oximetry during anesthesia induction and tracheal intubation. Tolerable apnea time will be defined as the duration from the end of ventilation after intubation to a decrease in peripheral oxygen saturation (SpO₂) to 94%. The primary objective is to assess the association between ORI warning time and tolerable apnea time. Secondary objectives include evaluating the association between ORI values, arterial blood gas parameters at predefined time points, and the Clinical Frailty Scale.

NCT Number	NCT07326293
Lead Sponsor	Ankara City Hospital Bilkent
Conditions	Desaturation, Apnea, Hypoxia, Oxygen Reserve Index
Enrollment	44 participants
Start Date	2025-12-16
Primary Completion	2026-02-16 (estimated)
Study Completion	2026-02-16 (estimated)
Updated on ClinicalTrials.gov	2026-01-08