Clinical Trial

Adaptive Radiotherapy for Genitourinary Cancers

Study acronym: SMART-B01
Recruiting
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Summary
The goal of this clinical trial is to learn if adaptive radiation boost works to treat genitourinary cancers, esp. in the context of prostate cancer patients with post-prostatectomy local relapse and bladder cancer patients with bladder-conserving treatment. It will also learn about the safety and efficacy of adaptive boost. The main questions it aims to answer are: Does adaptive boost lower the toxicities? Does adaptive boost maintain or improve the clinical efficacy? Participants will: Undergo adaptive boost on 1.5-Tesla MR-Linac Visit the clinic once every 2 weeks during RT, and every 3 months post-ART Keep a regular QOL questinnaire completion
Trial Details
NCT Number NCT07324798
Lead Sponsor Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Conditions Prostate Cancer (Post Prostatectomy), Bladder Cancer
Enrollment 60 participants
Start Date 2024-12-01
Primary Completion 2028-12-31 (estimated)
Study Completion 2028-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-07