Clinical Trial

Abuse Liability for Eight Electronic Nicotine Products

Not Yet Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated January 7, 2026 (before its estimated April 15, 2026 completion). Its status may not reflect the trial's current state.
Summary
This will be a randomized, open-label, 8-way crossover, single-site study designed to evaluate elements of abuse liability (AL), including subjective effects and physiological measures (pharmacodynamics \[PD\]), and plasma nicotine uptake (pharmacokinetics \[PK\]) during and following ad libitum use of Electronic Nicotine Delivery System (ENDS) investigational products (IPs) in a confinement setting by generally healthy adult smokers of combustible cigarettes and dual users of cigarettes and ENDS products.
Trial Details
NCT Number NCT07323511
Lead Sponsor RAI Services Company
Conditions Smoking, Smoking Behaviors, Tobacco Use, Tobacco Smoking
Enrollment 70 participants
Start Date 2026-02-15
Primary Completion 2026-04-15 (estimated)
Study Completion 2026-09-15 (estimated)
Updated on ClinicalTrials.gov 2026-01-07