Clinical Trial

Preoperative Lymphocyte-to-Monocyte Ratio and Postoperative Delirium by Frailty Status in Older Surgical Patients

Completed
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Summary
Both frailty and a reduced preoperative lymphocyte-to-monocyte ratio (LMR) are known risk factors for postoperative delirium (POD). However, whether the relationship between LMR and POD varies by frailty status remains unclear. This study aimed to evaluate the frailty-stratified association between preoperative LMR and POD in older surgical patients.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-12-23.
Trial Details
NCT Number NCT07322744
Lead Sponsor Chinese PLA General Hospital
Conditions Postoperative Delirium (POD), Frailty at Older Adults, Lymphocyte
Enrollment 6,475 participants
Start Date 2020-04-01
Primary Completion 2022-04-30 (estimated)
Study Completion 2023-12-30 (estimated)
Updated on ClinicalTrials.gov 2026-01-09