The Effect of Massage on Sleep Quality, Stress, Comfort, and Vital Signs in Preterm Infants

This randomized controlled trial investigates the effects of massage therapy on sleep quality, stress, comfort, and vital signs in preterm infants (gestational age 35-37 weeks) admitted to the Neonatal Intensive Care Unit (NICU) at Van YYU Training and Research Hospital. Infants in the intervention group will receive a 15-minute massage three times a day for three consecutive days, while the control group will receive standard care. Data will be collected using the Premature Infant Comfort Scale, Neonatal Stress Scale, actigraphy for sleep monitoring, and vital sign measurements. The study aims to determine whether massage therapy can improve the overall well-being and development of preterm infants in NICU settings.

NCT Number	NCT07322731
Lead Sponsor	Yuzuncu Yil University
Conditions	Premature Infants, Sleep Quality, İnfant Stress, İnfant Comfort, Vital Signs, NICU
Enrollment	40 participants
Start Date	2025-08-15
Primary Completion	2026-05-15 (estimated)
Study Completion	2026-06-15 (estimated)
Updated on ClinicalTrials.gov	2026-01-07