Kaempferol Absorption and Pharmacokinetics Evaluation

This study is a multi-site clinical trial designed to evaluate how the body absorbs and processes Kaempferol, a naturally occurring compound found in many plant-based foods. The primary purpose of the study is to measure the pharmacokinetics and biological absorption of Kaempferol in healthy adults. Participants will receive Kaempferol and undergo scheduled blood and urine collections over a short study period. These samples will be used to measure Kaempferol levels in the body and to assess safety and tolerability. In addition, selected biological samples will be analyzed to explore molecular changes associated with Kaempferol exposure using advanced laboratory methods. The study will be conducted at multiple research centers in the United States using a standardized protocol to ensure consistency across sites. The information collected will help improve understanding of how Kaempferol is absorbed and metabolized in humans and will support future research and regulatory evaluation.

NCT Number	NCT07322406
Lead Sponsor	University of Pittsburgh Collaborators: Otsuka Pharmaceutical Co., Ltd.
Conditions	No Disease, Mitochondria Health, Longevity, Pharmacokinetics and Biological Absorption of Kaempferol in Healthy Adult, Healthy Volunteers
Enrollment	120 participants
Start Date	2025-12-09
Primary Completion	2026-12-09 (estimated)
Study Completion	2027-12-22 (estimated)
Updated on ClinicalTrials.gov	2026-03-23