Clinical Trial

The Effect of Exercise Training on lncRNA Expression in Rheumatoid Arthritis

Recruiting
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Summary
The goal of this observational study is to examine the effects of traditional respiratory rehabilitation and respiratory muscle strengthening training added to this program at the genetic level in in patients with rheumatoid arthritis-associated interstitial lung disease. The main questions it aims to answer are: * Does respiratory muscle strengthening exercise added to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have additional benefits on rehabilitation outcome measures such as exercise capacity, shortness of breath, and muscle strength? * Does the gain obtained with respiratory muscle strengthening iin patients with rheumatoid arthritis-associated interstitial lung disease increase the quality of life of patients and have a positive effect on their psychological state? * Does respiratory rehabilitation applied to iin patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Does respiratory muscle strengthening training applied in addition to respiratory rehabilitation in patients with rheumatoid arthritis-associated interstitial lung disease have an effect on genetic changes? * Participants will be included in two different respiratory rehabilitation programs with and without respiratory muscle training, and pre- and post- treatment rehabilitation criteria and genetic changes will be compared.
Trial Details
NCT Number NCT07320846
Lead Sponsor Saglik Bilimleri Universitesi
Conditions Exercise, Pulmonary Rehabilitation, Interstitial Lung Disease, Long Noncoding RNA, Inspiratory Muscle Training, Rheumatoid Arthritis
Enrollment 39 participants
Start Date 2024-05-18
Primary Completion 2025-10-01 (estimated)
Study Completion 2026-03-12 (estimated)
Updated on ClinicalTrials.gov 2026-01-06