Clinical Trial

Advanced PRF vs PRF for Gap Filling in Immediate Implants

Study acronym: A-PRF vs PRF
Active, Not Recruiting
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Summary
Study type: Clinical Trial Goal: The goal of this clinical trial is to learn if Advanced Platelet-Rich Fibrin (A-PRF) versus traditional Platelet-Rich Fibrin (PRF) can improve bone healing and soft tissue outcomes in patients undergoing immediate dental implant placement. Main questions it aims to answer: Does A-PRF provide greater buccal bone preservation compared to PRF after immediate implant placement? Does A-PRF improve soft tissue healing and reduce postoperative complications compared to PRF? Comparison group: Researchers will compare A-PRF to PRF as a gap-filling material in immediate implants to see if A-PRF results in better bone and soft tissue outcomes. Participants will: Undergo tooth extraction followed by immediate implant placement Receive either A-PRF or PRF as the gap-filling material in the implant site Have CBCT scans at baseline and 6 months to measure bone thickness Have clinical assessments of soft tissue healing and implant stability Attend follow-up visits at 1 week, 1 month, 3 months, and 6 months post-surgery
Trial Details
NCT Number NCT07319494
Lead Sponsor Beni-Suef University
Conditions Comparison of Advanced Platelet-Rich Fibrin Versus Platelet-Rich Fibrin as a Gap-filling Material
Enrollment 16 participants
Start Date 2025-06-25
Primary Completion 2025-11-26 (estimated)
Study Completion 2026-02-15 (estimated)
Updated on ClinicalTrials.gov 2026-01-06