EFFECT OF SAPHENOUS NERVE RELEASE ON PATIENTS WITH PATELLOFEMORAL PAIN SYNDROME

Patellofemoral Pain Syndrome (PFPS) is a frequent cause of anterior knee pain in young, physically active individuals, especially females, and is commonly managed with quadriceps and hip-focused exercises. However, the role of neural factors has been largely overlooked. The saphenous nerve, which supplies sensation to the anteromedial knee, may become irritated or entrapped and contribute to pain and neuromuscular dysfunction in PFPS. This study suggests that manual therapy targeting the saphenous nerve could improve pain, function, and balance, providing a more holistic approach to PFPS rehabilitation.

NCT Number	NCT07318987
Lead Sponsor	Cairo University
Conditions	Patellofemoral Pain Syndrome
Enrollment	36 participants
Start Date	2025-10-10
Primary Completion	2026-01-10 (estimated)
Study Completion	2026-01-27 (estimated)
Updated on ClinicalTrials.gov	2026-01-06