Clinical Trial

Autologous Tenon's Capsule Graft for Refractory Macular Holes

Study acronym: ATCG-RMH
Recruiting
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Record status
This record was last updated January 6, 2026 (before its estimated June 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
This prospective interventional study evaluates the anatomical and functional outcomes of autologous Tenon's capsule grafting in patients with refractory full-thickness macular holes. Eligible patients include those with chronic large macular holes (\>400 µm) or persistent holes following prior pars plana vitrectomy with internal limiting membrane peeling and gas tamponade. Anatomical closure will be assessed using spectral-domain optical coherence tomography, and functional outcomes will be evaluated by best-corrected visual acuity over a 3-month follow-up period.
Trial Details
NCT Number NCT07318961
Lead Sponsor Benha University
Conditions Macular Hole Surgery
Enrollment 20 participants
Start Date 2025-12-14
Primary Completion 2026-06-01 (estimated)
Study Completion 2026-06-03 (estimated)
Updated on ClinicalTrials.gov 2026-01-06