Comparative Evaluation of the Effect of pH Adjustment of the Solution of Articaine With Epinephrine on the Efficacy of Jet Anesthesia

The purpose of this study is to evaluate the effect of pH adjustment of the solution of articaine 4% with epinephrine 1:100.00, on the efficacy of anesthesia with the usage of a local anesthesia device that is needle-free (Comfort-In), and uses pressure implementation. An additional purpose of the study is to evaluate the efficacy of the device and its acceptance by the patients.

NCT Number	NCT07318311
Lead Sponsor	Aristotle University Of Thessaloniki
Conditions	Comparative Evaluation of the Effect of pH Adjustment of the Solution of Articaine With Epinephrine on the Efficacy of Jet Anesthesia
Enrollment	45 participants
Start Date	2022-08-01
Primary Completion	2022-10-30 (estimated)
Study Completion	2022-11-07 (estimated)
Updated on ClinicalTrials.gov	2026-01-05