Clinical Trial

Sensitivity to Ovarian Hormones and Depression in Adolescents

Study acronym: SOHDA
Not Yet Recruiting
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Summary
The goal of this observational study is to learn about the relationship between changes in ovarian hormones (estrogen and progesterone) and adolescent depression. The main question it aims to answer is: Can we identify a subset adolescents assigned female at birth with a history of depression who are particularly sensitive to changes in ovarian hormones? Participants will be monitoring daily absolute ovarian hormone levels at home using the Mira Analyzer and answer online survey questions about their mental health for 90 days.
Trial Details
NCT Number NCT07317895
Lead Sponsor University of Calgary
Conditions Depressed
Enrollment 94 participants
Start Date 2026-03-01
Primary Completion 2027-03-31 (estimated)
Study Completion 2027-08-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-05