Clinical Trial

Predictive Score for the Success of Discontinuation of Renal Replacement Therapy (RRT) in Intensive Care

Study acronym: SERENA
Completed
View on ClinicalTrials.gov →
Summary
The goal of this observational study is to evaluate when renal replacement therapy (RRT) can be safely discontinued in intensive care unit (ICU) patients with acute kidney injury (AKI). The main question it aims to answer is: Can the UNDERSCORE predictive score accurately identify ICU patients with AKI who can successfully stop RRT without needing restart or experiencing early death? Using routinely collected clinical data from the AP-HP Health Data Warehouse, the study will follow ICU patients with AKI treated with RRT to assess whether the UNDERSCORE score predicts successful RRT discontinuation within 7 days.
Trial Details
NCT Number NCT07317362
Lead Sponsor Assistance Publique - Hôpitaux de Paris
Conditions D012139, D003924
Enrollment 5,976 participants
Start Date 2025-11-19
Primary Completion 2025-12-15 (estimated)
Study Completion 2025-12-15 (estimated)
Updated on ClinicalTrials.gov 2026-01-05