HUmanitas PROtontherapy (HU-PRO)

Proton therapy is a cancer treatment, similar to the more commonly used radiation therapy. It uses radiation to destroy cancer cells and helps control the disease in the treated area. However, when proton therapy is compared with standard radiation therapy, many studies show fewer side effects and better disease control. This is due to the unique physical properties of the particles used in proton therapy. At present, in Italy, this innovative treatment is available only for selected diseases, as defined by national guidelines. For this reason, it is very important to collect as much data as possible to support the further development of proton therapy and to improve treatment safety and effectiveness.

NCT Number	NCT07317245
Lead Sponsor	Istituto Clinico Humanitas
Conditions	Cancer, Proton Therapy
Enrollment	500 participants
Start Date	2026-01-12
Primary Completion	2036-01 (estimated)
Study Completion	2036-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-21