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Eccentric Cycling in Multiple Sclerosis Rehabilitation

StatusActive, Not Recruiting
PhaseNot applicable
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 60 days later Oct 2026 → Dec 30, 2026
Primary endpoints added 2 → 4 primary endpoints
See other at-risk trials from University of Liege

Record History

See every version on ClinicalTrials.gov ↗

  1. Primary endpoint(s) modified Show 4 more changesShow less
    • Eligibility criteria shortened, about 8 words
    • Secondary endpoints: 11 to 12
    • Study description expanded, about 122 words
    • Site details revised
  2. Trial status changed: Not Yet Recruiting → Active, Not Recruiting Show 6 more changesShow less
    • Primary completion pushed from Oct 2026 to Dec 30, 2026
    • Study completion pushed from Dec 2026 to Jul 31, 2027
    • Start date changed from estimate of Jan 2026 to Mar 27, 2026
    • Eligibility criteria expanded, about 12 words
    • Secondary endpoints: details revised at 4 of 11 entries
    • Site details revised
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The project aims to optimise functional rehabilitation programmes for people with multiple sclerosis. Investigators are proposing eccentric cycling as a new exercise modality for treating these patients. Based on previous results in healthy subjects, investigators will attempt to define the optimal parameters of this new modality (in terms of duration, intensity, frequency, etc.). Investigators also aim to demonstrate the effectiveness of this training (compared to conventional training) in improving muscle function, functional capacity, perception of chronic fatigue, quality of life, physical condition, and neurological and cognitive function.
Trial Details
NCT Number NCT07316764
Lead Sponsor University of Liege
Collaborators: University Hospital Sart Tilman, Liege
Conditions
(from sponsor)		 Multiple Sclerosis, Rehabilitation, Neuro-Degenerative Disease, Neurorehabilitation
Related terms Multiple Sclerosis
Enrollment 60 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov