Eccentric Cycling in Multiple Sclerosis Rehabilitation

The project aims to optimise functional rehabilitation programmes for people with multiple sclerosis. Investigators are proposing eccentric cycling as a new exercise modality for treating these patients. Based on previous results in healthy subjects, investigators will attempt to define the optimal parameters of this new modality (in terms of duration, intensity, frequency, etc.). Investigators also aim to demonstrate the effectiveness of this training (compared to conventional training) in improving muscle function, functional capacity, perception of chronic fatigue, quality of life, physical condition, and neurological and cognitive function.

NCT Number	NCT07316764
Lead Sponsor	University of Liege Collaborators: University Hospital Sart Tilman, Liege
Conditions	Multiple Sclerosis, Rehabilitation, Neuro-Degenerative Disease, Neurorehabilitation
Enrollment	60 participants
Start Date	2026-01
Primary Completion	2026-10 (estimated)
Study Completion	2026-12 (estimated)
Updated on ClinicalTrials.gov	2026-01-05