Passive Fit of Implant-Supported Complete-Arch Prostheses Using Digital Workflows

The goal of this clinical trial is to evaluate and compare three digital workflows for the fabrication of definitive implant-supported full-arch prostheses in adult patients requiring fixed implant rehabilitation. The main questions it aims to answer are: * Does an automated AI-assisted digital workflow improve the passive fit of definitive full-arch implant-supported prostheses compared with manual and splint-guided alignment workflows? * Are there differences in marginal, geometric, mechanical, and radiographic passivity among the three digital workflows? Researchers will compare manual CBCT-STL alignment, splint-guided alignment, and automated AI-assisted CBCT-STL alignment to see if the degree of digital workflow automation affects the passive fit of definitive full-arch implant-supported prostheses. Participants will: * Be adults (18 years and older) indicated for fixed implant-supported full-arch rehabilitation. * Receive a definitive, screw-retained, full-arch implant-supported prosthesis fabricated using one of the three assigned digital workflows. * Undergo standardized clinical and radiographic assessments at the time of definitive prosthesis placement to evaluate prosthesis passive fit.

NCT Number	NCT07315620
Lead Sponsor	Universidad Complutense de Madrid
Conditions	Prosthesis and Implant Dentistry
Enrollment	30 participants
Start Date	2026-01-01
Primary Completion	2026-12-01 (estimated)
Study Completion	2027-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-09