Clinical Trial

A Study on the Changes of Glucose Metabolism and Exocrine Function in Patients With Chronic Pancreatitis

Recruiting Early Phase 1
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Summary
This study aims to investigate the impact of pancreatic exocrine insufficiency on the glucose profile and pancreatic and gastrointestinal endocrine hormones in patients with chronic pancreatitis through pancreatic enzyme intervention in a reverse manner. The primary objective is to observe the changes in glucose profile following pancreatic enzyme intervention in patients with chronic pancreatitis complicated by exocrine insufficiency and normal glucose metabolism. The secondary objective is to observe the changes in pancreatic endocrine and exocrine functions and gastrointestinal endocrine hormone levels following pancreatic enzyme intervention in patients with chronic pancreatitis complicated by exocrine insufficiency and normal glucose metabolism.
Trial Details
NCT Number NCT07314489
Lead Sponsor Shanghai Changzheng Hospital
Conditions Chronic Pancreatitis Pancreatic Exocrine Insufficiency Blood Glucose
Enrollment 80 participants
Start Date 2025-04-01
Primary Completion 2026-12-31 (estimated)
Study Completion 2035-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-01-02