Clinical Trial

The Liquid Embolic Agent for the Treatment of Brain Arteriovenous Malformation

Study acronym: PARTNER
Recruiting
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Summary
This study is designed as a prospective, multi-center, open-label, non-inferiority, randomized controlled clinical trial. The control device is Onyx Liquid Embolic System marketed by Micro Therapeutics Inc. DBA ev3 Neurovascular (NMPA (J) 20173136690). According to the inclusion and exclusion criteria specified in this trial protocol, approximately 116 subjects with brain arteriovenous malformation will be enrolled for interventional embolization treatment. The subjects will undergo follow-up before the surgery, after device implantation, at discharge, 1 month (± 7 days), 6 months (± 30 days), and 12 months (± 60 days) after the first embolization. When necessary, unscheduled follow-up will be conducted to record various indicators for evaluating the safety and effectiveness of liquid embolic agents in the treatment of brain arteriovenous malformations.
Trial Details
NCT Number NCT07314047
Lead Sponsor MicroPort NeuroTech Co., Ltd.
Conditions Brain Arteriovenous Malformation, Arteriovenous Fistula
Enrollment 116 participants
Start Date 2024-05-28
Primary Completion 2025-05-28 (estimated)
Study Completion 2026-05-28 (estimated)
Updated on ClinicalTrials.gov 2026-01-02