This population-based retrospective cohort study aimed to evaluate the appropriateness of antiplatelet therapy use among older adults with all-cause dementia and across different dementia subtypes. Medical records of patients aged 65 years and older who were evaluated at a tertiary-level geriatric outpatient clinic were reviewed. Dementia subtypes were classified according to internationally accepted diagnostic criteria. Patterns of antiplatelet use were assessed in accordance with current guideline recommendations. The study sought to determine the appropriateness of antiplatelet use across dementia subtypes and to describe real-world prescribing practices in this population.