Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology

Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity. Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment. However, few studies have analyzed the long-term reproductive outcomes of these interventions, nor how patients ultimately use or do not use the FP options once in remission. This project aims to better understand the effectiveness, utilization, and psychological impacts of these strategies. This work is part of an effort to understand and evaluate fertility preservation practices implemented for women of reproductive age undergoing cancer treatment at the Amiens-Picardie University Hospital (CHU). Its objective is to document patient pathways, clinical decisions, techniques employed, and reproductive outcomes observed after remission, in order to identify potential areas for improvement in the support and follow-up of these patients, thereby enhancing the overall quality and coordination of care. This work is conducted alongside the development of a fertility observatory at the Department of Medicine and Reproductive Biology, CHU Amiens-Picardie.

NCT Number	NCT07312058
Lead Sponsor	Centre Hospitalier Universitaire, Amiens
Conditions	Fertility Preservation, Cancer Remission, Reproductive Outcomes, Reproductive Health, Oncology, Fertility Counseling, Assisted Reproductive Technology, Psychological Impact +5 more
Enrollment	102 participants
Start Date	2025-12-17
Primary Completion	2027-01 (estimated)
Study Completion	2027-01 (estimated)
Updated on ClinicalTrials.gov	2026-01-16