Development and Validation of a cCTA and Biomarker Based Risk Model for Coronary Revascularization in Elderly Patients With Coronary Artery Disease

This study is a prospective multi-center observational cohort involving elderly patients (≥70 years old) with multi-vessel coronary disease identified by coronary computed tomography angiography (cCTA) and scheduled for invasive coronary angiography. Data collection about cCTA, frailty and biomarkers and two-year follow-up will be conducted to develop and validate a risk model of coronary revascularization.

NCT Number	NCT07311954
Lead Sponsor	China National Center for Cardiovascular Diseases Collaborators: Central China Fuwai Hospital of Zhengzhou University, Chinese Academy of Medical Sciences, Fuwai Hospital
Conditions	Coronary Artery Disease, Elderly (Aged >70)
Enrollment	800 participants
Start Date	2026-01-01
Primary Completion	2029-01-01 (estimated)
Study Completion	2029-01-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-31