Clinical Trial

HELIOS: Human Embryo Illumination to Enhance Development

Study acronym: HELIOS
Active, Not Recruiting
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Summary
Embryos need a lot of energy to grow, but as women get older, the "power plants" of the cells (called mitochondria) don't work as well. This makes it harder for embryos to develop normally. One possible way to help is with a gentle light treatment called photobiomodulation (PBM). This uses a special type of red light that boosts energy production in cells and helps them stay healthy. This study will test whether adding this light treatment during in vitro fertilization (IVF) can improve embryo growth and pregnancy chances.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2025-12-16.
Status change: Recruiting → Active, Not Recruiting 2026-03-23
Trial Details
NCT Number NCT07311928
Lead Sponsor Columbia University
Conditions IVF Outcomes
Enrollment 200 participants
Start Date 2025-12-03
Primary Completion 2027-06-01 (estimated)
Study Completion 2028-06-01 (estimated)
Updated on ClinicalTrials.gov 2026-03-25