Clinical Trial

LLM-Generated Lay Summaries for Brain MRI Reports

Study acronym: CLEAR-HEAD
Completed
View on ClinicalTrials.gov →
Summary
The goal of this clinical trial is to learn if a summary written by artificial intelligence (AI) helps adults understand brain MRI reports for headaches. The main question it aims to answer is: "Does adding a simple summary help readers correctly understand if a cause for the headache was found in the report?" Researchers will compare standard MRI reports to reports that include an AI-generated explanation to see if the extra summary improves understanding. Participants will: Read 6 fictional brain MRI reports online. Answer questions to check if they understood the results. Rate their satisfaction and if they feel they would need to ask a doctor for help.
Protocol Amendment History 5 changes
critical Trial status changed: Enrolling by Invitation → Completed 2026-05-14
notable Enrollment increased: 1200 -> 2727 participants 2026-05-14
critical Trial status changed: Not Yet Recruiting → Enrolling by Invitation 2026-05-05
notable Primary completion pushed: 2026-02-10 -> 2026-04-30 2026-05-05
minor Completion pushed: 2026-02-25 -> 2026-04-30 2026-05-05
Trial Details
NCT Number NCT07310394
Lead Sponsor University Hospital, Lille
Collaborators: Direction Générale de l'Offre de Soins
Conditions Headache
Enrollment 2,727 participants
Start Date 2026-03-25
Primary Completion 2026-04-30 (estimated)
Study Completion 2026-04-30 (estimated)
Updated on ClinicalTrials.gov 2026-05-13