Tizanidine and Acoustic Reflex

The goal of this clinical trial is to learn how the muscle relaxant tizanidine affects the acoustic reflex in adults. The acoustic reflex is a natural protection system of the ear that helps reduce the impact of loud sounds. It is not known whether tizanidine changes how this reflex works. The main question this study aims to answer is: Does taking tizanidine for 1 week change acoustic reflex thresholds in the same person when comparing before and after treatment? Participants who receive tizanidine will undergo hearing and acoustic reflex tests before treatment and again at the end of the treatment period.

NCT Number	NCT07309354
Lead Sponsor	Uşak University
Conditions	Reflex, Acoustic, Hearing
Enrollment	48 participants
Start Date	2025-07-15
Primary Completion	2026-04-15 (estimated)
Study Completion	2026-04-26 (estimated)
Updated on ClinicalTrials.gov	2026-05-07