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Impact of Perioperative Dexmedetomidine and Esketamine on Postoperative Quality of Recovery

StatusRecruiting
PhasePhase 4
Started
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Record History

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  1. Primary completion pushed from Mar 2026 to Mar 2027v3 Show 4 more changesShow less
    • Recruitment opened
    • Study completion pushed from Apr 2026 to Apr 2027
    • Start date changed from estimate of Dec 2025 to Jan 5, 2026
    • Site details revised
  2. Study description shortened, about 7 wordsv2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
For patients after surgery, quality of recovery has significant impacts on the prognosis, quality of life, and rational allocation of medical resources. Dexmedetomidine and esketamine have each been used during the perioperative period and improved postoperative analgesia and subjective sleep quality. This 2x2 factorial trial is designed to explore the effects of dexmedetomidine, esketamine, and their combination on the quality of recovery in patients recovering from surgery under general anesthesia.
Trial Details
NCT Number NCT07308756
Lead Sponsor Peking University First Hospital
Conditions
(from sponsor)		 General Anesthesia, Surgery, Dexmedetomidine, Esketamine, Quality of Recovery
Enrollment 316 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov