Comparison Between Two Methods for Renal Stone Treatment Mini Percutaneous Nephrolithotomy and Flexible Ureteroscopy With Suction Sheath

This study aims to compare the efficacy and safety of two modern, minimally invasive surgical techniques for the removal of kidney stones: Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Flexible Ureteroscopy (FURS) with Flexible and navigable suction sheath The primary objective is to determine which procedure results in a higher stone-free rate, as measured by post-operative imaging. Secondary objectives include comparing operative time, hospitalization length andcomplication rates between the two treatment groups. Patients with two to three centimeter kidney stones who are candidates for either procedure will be randomly assigned to undergo either Mini-PCNL or suctioning FURS. The outcomes will be critically assessed to help establish a higher level of evidence for guiding surgical management of kidney stones.

NCT Number	NCT07306819
Lead Sponsor	Ain Shams University
Conditions	Stone;Renal, Stone, Urinary, Stone, Kidney, Stone Clearance
Enrollment	120 participants
Start Date	2025-10-15
Primary Completion	2026-08-15 (estimated)
Study Completion	2026-09-15 (estimated)
Updated on ClinicalTrials.gov	2025-12-29