Prevalence of Abnormal Haemoglobin Variants in Metropolitan Chattogram, Bangladesh

Hemoglobinopathies are inherited disorders that affect haemoglobin and pose a considerable global health challenge. This research addresses the knowledge gap regarding the prevalence of a typical haemoglobin fraction within urban populations by testing the HbA1c test in capillary electrophoresis. Participants will be recruited with careful ethical considerations and informed consent will be obtained. The screening will utilize laboratory techniques to detect abnormal haemoglobin fractions through testing. Statistical methods will be used for data analysis to assess prevalence rates and pinpoint specific haemoglobin variants while considering demographic factors. The project's milestones include planning the study, collecting data (from January 2021 to June 2025), conducting analyses, preparing reports and sharing the findings.

NCT Number	NCT07305181
Lead Sponsor	Bangladesh Bioscience Research Group Collaborators: Chattogram International Dental College, Chittagong Medical College and Hospital, Bangladesh Medical University
Conditions	HbE Trait, Hemoglobinopathies
Enrollment	8,400 participants
Start Date	2021-01-01
Primary Completion	2025-06-30 (estimated)
Study Completion	2025-09-30 (estimated)
Updated on ClinicalTrials.gov	2025-12-26