Evaluation of Effectiveness of Closed-loop Spinal Cord Stimulation (CL-SCS) Therapy for Treatment of Chemotherapy Induced Peripheral Neuropathy

The goal of this observational study is to learn about the effectiveness of closed-loop spinal cord stimulation (CL-SCS) therapy for treatment of painful chemotherapy induced peripheral neuropathy. The closed-loop SCS (CL-SCS) system stimulates the nerves in the spinal cord, measures their responses and automatically adjust the stimulation level accordingly in real time for each delivered pulse.

NCT Number	NCT07304401
Lead Sponsor	Rijnstate Hospital Collaborators: Saluda Medical Pty Ltd
Conditions	Chemotherapy Induced Peripheral Neuropathy (CIPN), Neuropathic Pain
Enrollment	20 participants
Start Date	2025-12-01
Primary Completion	2028-12-01 (estimated)
Study Completion	2028-12-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-26