Clinical Trial

The Effects of Remimazolam on Cerebral Blood Flow Following General Anesthesia Induction

Completed Phase 3
View on ClinicalTrials.gov →
Summary
This study will enroll 40 subjects aged 18 years or older scheduled for elective surgery under general anesthesia with endotracheal intubation. Basic medical history information will be collected. Subjects will be divided into two groups of 20 each: a remimazolam group and a propofol group. The study period will span from one day before surgery to one day after surgery. The study will assess middle cerebral artery cerebral blood flow following general anesthesia induction and postoperative anesthesia recovery.
Protocol Amendment History 3 changes
critical Trial status changed: Not Yet Recruiting → Completed 2026-04-16
critical Phase changed: Phase 4 -> Phase 3 2026-04-16
notable Enrollment increased: 40 -> 52 participants 2026-04-16
Trial Details
NCT Number NCT07303985
Lead Sponsor Jun Zhang
Conditions Cerebral Blood Flow
Enrollment 52 participants
Start Date 2025-12-29
Primary Completion 2026-02-28 (estimated)
Study Completion 2026-03-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-15