Deep Brain Stimulation of the Anterior Cingulate Bundle (ACB) and the Ventral Anterior Limb of the Internal Capsule (vALIC) in Patients With Intractable Obsessive Compulsive Disorder (OCD)

This is a double blind pilot feasibility study, with a within subject crossover design of DBS of the anterior cingulate bundle(ACB) and the ventral anterior limb of the internal capsule(vALIC) in four patients with intractable OCD. Patients will be screened according to inclusion exclusion criteria listed above, approved by an independent Neuropsychiatric review board and informed consent obtained.

NCT Number	NCT07303946
Lead Sponsor	Rhode Island Hospital Collaborators: Brown University, Baylor College of Medicine, Butler Hospital
Conditions	Obsessive-Compulsive Disorder
Enrollment	4 participants
Start Date	2026-01
Primary Completion	2030-01 (estimated)
Study Completion	2031-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-26