Female Concussion Head Cooling

This research is being done to examine the benefits of a 28 day head cooling intervention on cognition, inflammation of the brain, sleep quality, menstrual symptom interaction, and mood in acutely concussed females. Brain cooling has been shown to cause temporary symptom relief after traumatic brain injury, but its implications for decreasing timeline of full concussion recovery, particularly in females during periods of confounding neuropsychological menstrual symptoms, remains unexplored.

NCT Number	NCT07303933
Lead Sponsor	Penn State University
Conditions	Concussion (Diagnosis), Concussion Post Syndrome, Concussion, Mild
Enrollment	32 participants
Start Date	2026-01-15
Primary Completion	2027-01-01 (estimated)
Study Completion	2027-01-01 (estimated)
Updated on ClinicalTrials.gov	2025-12-26