Track this trial free. DataLookout checks ClinicalTrials.gov daily and emails you which fields changed on NCT07303296 (status, enrollment, completion dates, endpoints, sites) when this record is updated. Free accounts track up to 5 trials.

Track this trial

Efficacy and Safety Study of Bilateral IVT Injection of GS010 at Two Dose Levels in LHON Patients

Study acronym: REVISE
StatusRecruiting
PhasePhase 2
Started
View on ClinicalTrials.gov ↗

Record History

  1. Trial status: Not Yet Recruiting to Recruiting
    • Start date changed from estimate of Jan 15, 2026 to Jan 22, 2026
    • Site details revised
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this Clinical trial is to assess the safety and efficacy of GS010 at two dose levels on visual acuity and retinal mitochondrial activity in patients affected with ND4 Leber Hereditary Optic Neuropathy (LHON)
Trial Details
NCT Number NCT07303296
Lead Sponsor GenSight Biologics
Conditions
(from sponsor)		 Leber Hereditary Optic Disease
Related terms Eye Diseases, Genetic Diseases, Inborn, Mitochondrial Diseases, Nervous System Diseases, Neurodegenerative Diseases, Optic Atrophy, Hereditary, Leber
Enrollment 14 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov