Functional MRI for Monitoring Progression and Assessing Trends in ILD

The main objective of this study is to investigate the utility of functional MRI to differentiate, characterize, and monitor subgroups of ILD. This can be broken down into three specific objectives: Determine if ILD features observed on high-resolution computed tomography (HRCT), such as ground glass opacities (GGO), are functionally different. Analyse MRI metrics within each subgroup to determine whether these metrics distinguish different ILDs. Assess MRI metrics longitudinally to see if these parameters change with disease progression, stability, or reversibility.

NCT Number	NCT07300696
Lead Sponsor	University Hospital Heidelberg Collaborators: German Center for Lung Research, Thoraxklinik-Heidelberg gGmbH, University Hospital Schleswig-Holstein
Conditions	Interstitial Lung Diseases (ILD)
Enrollment	200 participants
Start Date	2025-11-20
Primary Completion	2027-02 (estimated)
Study Completion	2027-07 (estimated)
Updated on ClinicalTrials.gov	2025-12-24