Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey

The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of sepsis in adult patients admitted to Intensive Care Units (ICUs) in Turkey. The main questions it aims to answer are: * Does the SOFA-2 score accurately predict 30-day mortality in ICU patients? * What is the prevalence of Sepsis-3 and septic shock in Turkish ICUs? Researchers will compare the new SOFA-2 score to the existing SOFA-1 score to see if the new score provides better predictive accuracy for patient outcomes. Participants will not receive any experimental intervention. Researchers will collect data from routine medical care, including: * Vital signs, laboratory test results, and details of organ support (such as mechanical ventilation or dialysis) during the first 24 hours of admission. * Survival status at 30 days.

NCT Number	NCT07300306
Lead Sponsor	Marmara University
Conditions	Sepsis, Septic Shock, Critical Illness, Organ Dysfunction
Enrollment	2,500 participants
Start Date	2026-05-04
Primary Completion	2026-06-23 (estimated)
Study Completion	2026-08 (estimated)
Updated on ClinicalTrials.gov	2026-08-05