Bioequivalence Study of Liquid Metformin (100 and 250 mg/mL) vs IR Tablets

This is an open-label, randomized, two-treatment, two-period crossover study evaluating the bioequivalence of liquid metformin formulations at 100 mg/mL and 250 mg/mL compared with immediate-release metformin tablets in healthy adult subjects. Each participant will receive both treatments in randomized sequence with an adequate washout interval between periods. Serial blood samples will be collected to assess metformin pharmacokinetics, and safety will be monitored throughout the study.

NCT Number	NCT07300033
Lead Sponsor	Aspargo Labs, Inc
Conditions	Healthy Volunteer
Enrollment	24 participants
Start Date	2026-05-15
Primary Completion	2026-07-15 (estimated)
Study Completion	2026-07-28 (estimated)
Updated on ClinicalTrials.gov	2025-12-23