Mechanisms of Maternal Immune Tolerance in Early Pregnancy

This study explores the mechanisms of maternal immune tolerance in early pregnancy by characterizing immune cell profiles and functional pathways during the first trimester. The goal is to identify immunological factors that support healthy gestation and prevent complications such as miscarriages.

NCT Number	NCT07297394
Lead Sponsor	University Hospital, Basel, Switzerland
Conditions	Pregnancy, Immune Tolerance, In Vitro Fertilization
Enrollment	100 participants
Start Date	2026-03-02
Primary Completion	2030-12 (estimated)
Study Completion	2030-12 (estimated)
Updated on ClinicalTrials.gov	2026-03-04