Clinical Trial

Effect of Sevoflurane vs Desflurane on Mechanical Power in Laparoscopic Cholecystectomy

Study acronym: VAPOR
Recruiting
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Record status
This record was last updated July 20, 2026 (before its estimated July 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
This single-center, prospective, randomized, assessor-blinded clinical trial aims to compare the effects of sevoflurane and desflurane anesthesia on intraoperative mechanical power in adult patients undergoing elective laparoscopic cholecystectomy. Mechanical power will be measured at three standardized time points using a validated formula, and secondary outcomes include driving pressure values and early postoperative respiratory complications (desaturation, laryngospasm, bronchospasm, cough).
Protocol Amendment History 2 changes
notable Primary completion pushed: 2026-04-30 -> 2026-07-30 2026-07-21
minor Completion pushed: 2026-05-30 -> 2026-08-30 2026-07-21
Trial Details
NCT Number NCT07295158
Lead Sponsor Konya City Hospital
Conditions Perioperative Respiratory Mechanics
Enrollment 138 participants
Start Date 2026-03-09
Primary Completion 2026-07-30 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-20