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Extracellular Vesicles for the Treatment of Syringomyelia

StatusActive, Not Recruiting
PhasePhase 1
Started
View on ClinicalTrials.gov ↗

Record History

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  1. Trial status changed: Recruiting → Active, Not Recruiting
    • Primary completion moved earlier from Dec 31, 2026 to May 7, 2026
    • Site details revised
    v3
  2. Start date changed from estimate of Dec 15, 2025 to Dec 23, 2025
    • Eligibility criteria revised
    v2
  3. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This is a open-label, single-arm, dose escalation phase I clinical trial. The goal of this clinical trial is to evaluate the safety and preliminary efficacy of Intrathecal injection human umbilical cord-derived mesenchymal stromal cell-derived extracellular vesicle (hUC-MSC-sEV) in syringomyelia.
Trial Details
NCT Number NCT07295067
Lead Sponsor Xuanwu Hospital, Beijing
Collaborators: Yisaier Medical Technology (shan xi) Co., Ltd.
Conditions
(from sponsor)		 Syringomyelia
Related terms Spinal Cord Injuries, Syringomyelia
Enrollment 18 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov