Clinical Trial

Sentinel Node Resection With or Without LECS After Noncurative ESD for EGC

Study acronym: Co-SNARE
Not Yet Recruiting
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Summary
For patients with non-curative resection after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC), complementary surgery is generally recommended. However, about 2/3 of patients have no remaining tumor in the stomach or regional lymph nodes. In this trial, Indocyanine Green (ICG)-guided lymphadenectomy with or without laparoscopic and endoscopic cooperative surgery (LECS) will be tested as a less invasive alternative in such cases. For patients with a primary radically resected EGC, ICG-guided lymphadenectomy alone will be performed. For patients with deep-margin positive EGC, ICG-guided lymphadenectomy and LECS will be performed, in order to ensure both local tumor control in the stomach and in regional nodes.
Trial Details
NCT Number NCT07295002
Lead Sponsor Region Stockholm
Conditions Early Gastric Cancer
Enrollment 10 participants
Start Date 2026-01-01
Primary Completion 2029-10-01 (estimated)
Study Completion 2029-10-01 (estimated)
Updated on ClinicalTrials.gov 2025-12-19