Peripheral Relative Refractive Power of Orthokeratology Lenses

Orthokeratology (OK) has been demonstrated to be an effective intervention for slowing axial elongation in children with myopia. The proposed mechanism of action is the induction of peripheral myopic defocus, which reduces relative peripheral hyperopia on the retina. This study aims to evaluate changes in relative peripheral retinal refraction before and after OK lens wear using wide-field multispectral retinal refractive topography. The study will also investigate the relationship between these retinal refractive changes and the effectiveness of OK in controlling axial elongation.

NCT Number	NCT07294404
Lead Sponsor	Tianjin Eye Hospital
Conditions	Myopia, Myopia; Refractive Error
Enrollment	53 participants
Start Date	2020-01-10
Primary Completion	2021-06-15 (estimated)
Study Completion	2021-10-19 (estimated)
Updated on ClinicalTrials.gov	2026-03-02