TAP Block Versus ESP Block in Patients Undergoing Elective Cesarean Section: a Randomized Controlled Trial

StatusCompleted
PhaseNot applicable
Started

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Record History

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  1. Minor Trial completed
    • Primary completion date changed from estimate of Oct 2027 to Oct 9, 2026
    • Eligibility criteria expanded, about 7 words
    • Site details revised
  2. Notable Recruitment opened
    • Study sites: 0 to 1
    • Start date changed from estimate of Jan 2026 to Jan 7, 2026
    v3
  3. Notable Enrollment target: 156 to 90v2
  4. Minor Study First Submitted
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study is comparing two types of pain relief techniques-TAP block and ESP block-for women having an elective cesarean section. Both techniques involve injecting local anesthetic under ultrasound guidance to numb nerves and reduce pain after surgery. The TAP block mainly relieves pain in the abdominal wall, while the ESP block may reduce both abdominal wall and deeper, organ-related pain. The main goal is to see if there's a difference in pain at rest six hours after surgery. The study will also look at pain at later time points, the amount of opioid medication needed, how quickly women can walk, and when they start breastfeeding. A total of 156 women will be randomly assigned to receive one of the two blocks after standard spinal anesthesia. Pain will be measured using a simple 0-10 scale at 6, 12, and 24 hours, both at rest and during movement. The study follows strict ethical rules, ensures patient privacy, and all results-whether positive or negative-will be shared to help improve pain management after cesarean delivery.
Trial Details
NCT Number NCT07292662
Lead Sponsor University of Padova
Conditions
(from sponsor)
Cesarean Delivery, Regional Anesthesia Block
Enrollment 90 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov